Current members

I graduated in Biochemistry in 1994 from the University of Barcelona (UB), and received my PhD from the same University in 2000. At that time I moved to Dr Danny Reinberg’s lab (HHMI,USA) to perform my postdoctoral studies in epigenetic regulation of chromatin dynamics upon stress. In 2001, I became Howard Hughes Research associate, position I held until the end of 2005, when I returned to Spain as an I3P Researcher in Ferran Azorín lab (IBMB-CSIC). In 2006 I was appointed ICREA Researcher and in 2008 I became group leader of the Chromatin Biology Lab in the Cancer Epigenetics and Biology Program of IDIBELL (Barcelona). Since then, I have established a highly competitive laboratory centered on understanding the role of Sirtuins in the regulation of genome stability in response to stress, employing a combination of Biochemistry, Molecular and Cell Biology and Genetics. In mid 2019 the group moved to Josep Carreras Leukaemia Research Institute.

I obtained my degree in Biochemistry and Molecular Biology in 2000 from the Universitat Autònoma de Barcelona (UAB). I was awarded with a FI PhD fellowship (AGAUR, Catalan Govt) to work in Dra Àngels Fabra laboratory (LOM-IDIBELL) intenidentification of specific peptide sequences to redirect adenoviral vectors to metastatic prostate cancer cell lines. I completed my PhD in 2007 and from 2008 I have worked at the Chromatin Biology Lab as Research Assistant and senior researcher, where I provide support to the projects of the lab. 

During my Ph.D. at the University of Barcelona and Duke University, I studied in vivo epigenetic mechanisms of transcriptional regulation in immune cells. As a postdoctoral researcher at Rutgers University, I mostly focused my research effort on genome integrity with particular emphasis on the repression of jumping genes, the repair of DNA damage and chromosome segregation. I am passionate about chromatin biology and genome integrity. I am currently interested in understanding how epigenetics delineates cellular differentiation with the goal to translate this knowledge in the leukemia field, including the development of new strategies to combat leukemia and to reduce long-term side effects in survivors.

I obtained a bachelor’s degree in Biotechnologies at the University of L’Aquila (Italy) and my MSc in Medical Biotechnologies at the same University. I then moved to Germany where I conducted my PhD studies and 4 years of Post-doctoral Research at the Max Planck Institute for Heart and Lung Research in Bad Nauheim. In September 2021, I joined as senior researcher the Chromatin Biology Lab led by Dr. Alejandro Vaquero at the IJC. My research interest focuses on unveiling the molecular mechanisms employed by a class of histone deacetylases, collectively known as sirtuins, in different biological functions such as ageing, metabolism, cellular stress responses and cancer.

I received my Biotecnology degree in 2013 and a master´s degree in Celullar and Molecular Biology in 2014 in the University of Salamanca. In September 2015, I was awarded with FPI PhD studentship from MINECO to join the Chromatin Biology Lab. During my PhD thesis, we tried to understand the interplay between Sirt2 and MOF in the regulation of cell cycle progression. Since 2021, I am a Postdoctoral Researcher funded by Fundación Asociación Española Contra el Cáncer (AECC). 

I completed my undergraduate in Biotechnology followed by an MSc in Translational Medicine at the University of Barcelona. I then moved to Edinburgh, where I conducted my doctoral training studying the role of inflammatory pathways in cellular senescence at the Cancer Research UK Edinburgh Centre. More recently, I have pursued an MBA in Pharma and Biotech, complementing my academic background with an industrial perspective. As a postdoctoral researcher at the Chromatin Biology Lab, I investigate the specific contribution of Sirtuin ADP-ribosyltransferase and deacetylase activities in tumorigenesis.

I have a degree in Biochemistry and Biomedical Sciences (Universitat de Valencia) and a MSc in Neurosciences (Universitat de Barcelona). In 2019 I obtained a FPI fellowship to perform my PhD in Biomedicine under the supervision of Dr Alejandro Vaquero. The main aim of the project is to characterize the understudied MADPRT activity of Sirtuins, and specifically the enzymatic duality of SIRT6 and SIRT7  and their functional implications in aging and cancer.

I graduated in Biomedical Sciences at the Universitat Autònoma de Barcelona in 2020. In 2021, I obtained a MSc degree in Cytogenetics and Reproductive Biology at the same university. I am currently working in the Chromatin Biology group, led by Dr. Àlex Vaquero, where I plan to start my doctoral thesis. The project I am enrolled in is focused on the study of the role of Sirt7 in meiotic progression with the aim of providing new insights into the oncofertility field.

I am graduated in Biology from University of Oviedo. Then, I studied my MSc in Experimental Biomedicine at the University of Castilla La-Mancha, where I did my master research project focused on studying the role of the MAPK ERJ5 in response to gemcitabine in sarcomatoid models.

I am currently working as a PhD student at University of Barcelona (UB) in Biomedicine, with my PhD project focused on the study of the role of sirtuinas in response to stress and its implications in genomic stability and cancer, supervised by Dr. Alejandro Vaquero.

I received my degree in Biotechnology (Universitat de Girona) in 2018. I obtained a MSc degree in Biochemistry, Molecular Biology and Biomedicine at the Universitat Autònoma de Barcelona, where I worked in the Protein kinases and cancer research laboratory, directed by Dr. Jose M. Lizcano.  In March 2020 I was awarded a FI-AGAUR PhD fellowship granted (Generalitat de Catalunya) to perform my PhD in the Chromatin Biology lab.  My work aims to understand the role of SIRT7 in hematopoiesis and Leukemia.